Hidradenoma - a rare benign multilobulated tumor of the sweat gland, localized in the dermis, having both eccrine and apocrine differentiation. ICD-10 Code: D23.9
This rare tumor occurs equally in men and women; 80% of patients are over 40 years of age. Histochemical and electron microscopic studies have shown evidence of apocrine secretion. Ultrastructural studies have revealed a prominent Golgi complex and electron dense formations with "shedding" of the apical part of the cells (secretory granules) into the lumen of the duct.
Histologically, two main forms of hidradenoma are distinguished:
- Poroid (5%) with eccrine differentiation.
- Clear cell (95%) with apocrine differentiation.
In 50% of cases, hidradenoma is located on the skin of the face and scalp, in 21% on the skin of the extremities, and in 20% on the trunk.
Typically, hidradenoma presents as a cyst-like, well-defined dermal and/or subcutaneous nodule, bluish-gray in color, 1-3 cm in diameter, from which light or serosanguinous fluid may sometimes be discharged; in 15% of cases, the formation becomes ulcerated.
- Hidroacanthoma simplex
- Eccrine poroma
- Basal cell carcinoma
- Metastasis of renal cell carcinoma
- Tricholemmoma
- Dermatofibroma
Surgical excision and electrocoagulation are indicated for the treatment of hidradenoma.
The prognosis for hidradenoma is favorable.